This guidance just isn't intended to determine registration and/or submitting requirements or modify pharmacopoeial needs. This steering does not have an affect on the flexibility of your responsible regulatory company to ascertain unique registration/filing requirements regarding APIs throughout the context of promoting/production authorizations o
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[194] developed a product based on Darcy’s law so as to consider the swelling on the particles throughout the solid matrix and thus the constriction on the pores. They derived the following equation for the liquid penetration:nearby diffusion of particles after they have already been detached) disintegration. Peppas and Colombo [40] afterwards ex
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